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. Author manuscript; available in PMC: 2021 Oct 6.
Published in final edited form as: Cell Metab. 2020 Sep 21;32(4):619–628.e21. doi: 10.1016/j.cmet.2020.09.005
Category Parameter Comment Value
Model nflux Total flux number 26
nbalance Number of flux balance equations 9
nconstrain Number of flux constraints (not including free fluxes) 4
nmid Number of MID predictions 8
ndim Number of free fluxes 5
Fmin Minimal flux value 1
Fmax Maximal flux value 1000
Finput Value of supplement glucose flux in source tissue 150
Finfusion Value of glucose infusion flux 111.1
Fcirc,lac Value of lactate turnover flux 400
Fcirc,pyr Value of pyruvate turnover flux 70
Optimization nopt_repeat Repeat number to optimize the cost function 10
Lthreshold Objective value threshold to accept the fitting result 0.4
Sample ndiag Total sample number in solution space 3×106
FTCA,min Minimal TCA flux value 2
Ternary graph σternary Variance of gaussian kernel in ternary graph 0.15
nbin Resolution of ternary graph 256