. Author manuscript; available in PMC: 2021 Nov 1.

Published in final edited form as: Brain Behav Immun. 2020 Sep 20;90:353–363. doi: 10.1016/j.bbi.2020.09.012

Table 2.

CSF biomarkers by HIV serostatus

CSF Biomarker	HIV−	HIV+	p	d
Dopaminergic
Dopamine (pg/mL)	29.2 [7.3, 55.0]	33.6 [6.2, 66.3]	0.803	0.03
Homovanillic Acid (ng/mL)	9.0 [3.6, 25.6]	10.9 [4.4, 27.0]	0.408	0.11
Neuroinflammatory^a
Composite z-score	−0.4 (0.07)	0.3 (0.06)	<.001	1.02
IP-10 (pg/mL)	182.6 [127.3, 291.3]	431.8 [305.2, 683.2]	<.001	1.41
MCP-1 (pg/mL)	483 [345.1, 652.6]	513.7 [413.7, 761.8]	0.081	0.28
Neopterin (nmol/L)	6.1 [4.6, 8.3]	8.9 [5.9, 13.4]	0.001	0.53
Soluble CD14 (pg/mL)	68486 [47948, 103220]	94564 [61830, 121224]	<.001	0.55

Note. Values presented as median [IQR] or mean (SD). Biomarker values were log-transformed and standardized for statistical testing and Cohen’s d estimates.

Neuroinflammatory data available for a subset of participants (90 HIV+ and 66 HIV−).