Table 2.
Exposure | HTN cases (rate*) | HR (95% CI) | |||||
---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 2† | Model 3 | Model 4 | Model 5 | ||
Walking Volume (MET-hr/wk) | |||||||
0 (n=24,253) | 11,619 (45.8) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
>0–3.5 (n=16,122) | 7,549 (44.0) | 0.95 (0.93–0.98) | 0.98 (0.95–1.01) | --- | 0.97 (0.94–1.00) | 0.98 (0.95–1.01) | 0.98 (0.95–1.01) |
3.6–7.5 (n=22,791) | 10,343 (41.6) | 0.90 (0.88–0.93) | 0.95 (0.92–0.97) | --- | 0.96 (0.93–0.99) | 0.98 (0.95–1.01) | 0.97 (0.95–1.00) |
> 7.5 (n=20,269) | 8,719 (38.0) | 0.83 (0.81–0.86) | 0.89 (0.87–0.92) | --- | 0.91 (0.88–0.93) | 0.95 (0.92–0.98) | 0.93 (0.91–0.96) |
P trend | --- | <0.001 | <0.001 | --- | <0.001 | 0.036 | 0.001 |
Walking Speed (mph) | |||||||
<2 (n=8,971) | 4,389 (51.1) | 1.08 (1.04–1.11) | 1.07 (1.03–1.10) | 1.08 (1.04–1.12) | 1.06 (1.02–1.09) | 1.05 (1.01–1.09) | 1.05 (1.01–1.09) |
2–3 (n=29,782) | 13,680 (42.3) | 0.91 (0.88–0.93) | 0.95 (0.92–0.97) | 0.96 (0.93–0.98) | 0.95 (0.92–0.97) | 0.97 (0.95–1.00) | 0.97 (0.95–1.00) |
3–4 (n=19,305) | 8,124 (35.9) | 0.80 (0.78–0.83) | 0.86 (0.84–0.89) | 0.86 (0.83–0.89) | 0.89 (0.86–0.92) | 0.93 (0.90–0.95) | 0.90 (0.87–0.93) |
>4 (n=1,124) | 418 (30.1) | 0.71 (0.64–0.78) | 0.79 (0.71–0.87) | 0.77 (0.69–0.85) | 0.81 (0.74–0.90) | 0.89 (0.81–0.99) | 0.84 (0.76–0.93) |
P trend | --- | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Abbreviations as in Table 1.
Incidence rate, number of cases/ 1000 person-years.
Model 1: includes study component (WHI OS or CT), randomization to trial arms, age and race-ethnicity.
Model 2: includes Model 1 + education, alcohol, smoking, diet score, dietary sodium, diabetes, hyperlipidemia, cancer, and non-walking PA.
Model 2: includes Model 2 + walking duration (hours/week).
Model 3: includes Model 2 + Systolic and Diastolic BP.
Model 4: includes Model 2 + BMI.
Model 5: includes Model 2 + physical functioning score.