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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Hypertension. 2020 Sep 28;76(5):1435–1443. doi: 10.1161/HYPERTENSIONAHA.120.15839

Table 2.

Rates and relative risks of hypertension according to categories of walking volume and speed at baseline (N=83,435).

Exposure HTN cases (rate*) HR (95% CI)
Model 1 Model 2 Model 2 Model 3 Model 4 Model 5
Walking Volume (MET-hr/wk)
0 (n=24,253) 11,619 (45.8) 1.00 (ref) 1.00 (ref) 1.00 (ref) 1.00 (ref) 1.00 (ref) 1.00 (ref)
>0–3.5 (n=16,122) 7,549 (44.0) 0.95 (0.93–0.98) 0.98 (0.95–1.01) --- 0.97 (0.94–1.00) 0.98 (0.95–1.01) 0.98 (0.95–1.01)
3.6–7.5 (n=22,791) 10,343 (41.6) 0.90 (0.88–0.93) 0.95 (0.92–0.97) --- 0.96 (0.93–0.99) 0.98 (0.95–1.01) 0.97 (0.95–1.00)
> 7.5 (n=20,269) 8,719 (38.0) 0.83 (0.81–0.86) 0.89 (0.87–0.92) --- 0.91 (0.88–0.93) 0.95 (0.92–0.98) 0.93 (0.91–0.96)
P trend --- <0.001 <0.001 --- <0.001 0.036 0.001
Walking Speed (mph)
<2 (n=8,971) 4,389 (51.1) 1.08 (1.04–1.11) 1.07 (1.03–1.10) 1.08 (1.04–1.12) 1.06 (1.02–1.09) 1.05 (1.01–1.09) 1.05 (1.01–1.09)
2–3 (n=29,782) 13,680 (42.3) 0.91 (0.88–0.93) 0.95 (0.92–0.97) 0.96 (0.93–0.98) 0.95 (0.92–0.97) 0.97 (0.95–1.00) 0.97 (0.95–1.00)
3–4 (n=19,305) 8,124 (35.9) 0.80 (0.78–0.83) 0.86 (0.84–0.89) 0.86 (0.83–0.89) 0.89 (0.86–0.92) 0.93 (0.90–0.95) 0.90 (0.87–0.93)
>4 (n=1,124) 418 (30.1) 0.71 (0.64–0.78) 0.79 (0.71–0.87) 0.77 (0.69–0.85) 0.81 (0.74–0.90) 0.89 (0.81–0.99) 0.84 (0.76–0.93)
P trend --- <0.001 <0.001 <0.001 <0.001 <0.001 <0.001

Abbreviations as in Table 1.

*

Incidence rate, number of cases/ 1000 person-years.

Model 1: includes study component (WHI OS or CT), randomization to trial arms, age and race-ethnicity.

Model 2: includes Model 1 + education, alcohol, smoking, diet score, dietary sodium, diabetes, hyperlipidemia, cancer, and non-walking PA.

Model 2: includes Model 2 + walking duration (hours/week).

Model 3: includes Model 2 + Systolic and Diastolic BP.

Model 4: includes Model 2 + BMI.

Model 5: includes Model 2 + physical functioning score.