Table 1:
Characteristics of participants
| Level of Impairment | ||||||
|---|---|---|---|---|---|---|
| MCI | Dementia | |||||
| Aβ + | Aβ - | Total | Aβ + | Aβ - | Total | |
| Total N | 326 | 274 | 600 | 137 | 33 | 170 |
| Demographics | ||||||
| Age | 74.3 ± 5.7 (65–90) | 74.3 ± 5.7 (65–90) | 73.8 ± 5.54 (65–90) | 74.7 ± 6.09 (65–89) | 72 ± 5.98 (65–89) | 74.2 ± 6.15 (65–89) |
| Female | 132 (40.5%) | 138 (50.4%) | 270 (45.0%) | 57 (41.6%) | 15 (45.5%) | 72 (42.4%) |
| Years of Education | 16.1 ± 2.63 (12–20) | 16.3 ± 2.48 (12–20) | 16.2 ± 2.56 (12–20) | 15.6 ± 2.98 (6–20) | 16.2 ± 2.86 (12–20) | 15.7 ± 2.96* (6–20) |
| Caucasian | 299 (91.7%) | 239 (87.2%) | 538 (89.7%) | 125 (91.2%) | 27 (81.8%) | 152 (89.4%) |
| Has an enrolled SP | 140 (42.9%) | 77 (28.1%) | 217 (36.2%) | 60 (43.8%) | 10 (30.3%) | 70 (41.2%) |
| Cognitive/Functional Measures | ||||||
| MoCA score | 24.2 ± 3.38 (7–30) | 25.2 ± 2.88 (17–30) | 24.6 ± 3.21 (7–30) | 18.7 ± 5.45 (6–29) | 21.1 ± 5.82 (5–28) | 19.2 ± 5.57* (5–29) |
| MMSE score | 27.2 ± 2.38 (16–30) | 27.8 ± 2.17 (19–30) | 27.5 ± 2.3 (16–30) | 23.5 ± 4.2 (9–30) | 25.2 ± 4.69 (10–30) | 23.8 ± 4.33* (9–30) |
| CBB OCL score | 0.87 ± 0.12 (0.59–1.16) | 0.90 ± 0.15 (0.43–1.35) | 0.89 ± 0.13 (0.43–1.35) | 0.84 ± 0.10 (0.68–1.08) | 0.85 ± 0.13 (0.61–0.97) | 0.84 ± 0.11*(0.61–1.08) |
| Self-ECog score | 1.84 ± 0.61 (1–4) | 1.85 ± 0.59 (1–3.81) | 1.85 ± 0.6 (1–4) | 1.9 ± 0.65 (1–3.85) | 2.17 ± 0.71 (1.36–3.54) | 1.95 ± 0.67 (1–3.85) |
| SP-ECog score | 2.08 ± 0.64 (1.05–4) | 1.96 ± 0.71 (1–3.95) | 2.04 ± 0.67 (1–4) | 2.51 ± 0.79 (1.05–3.92) | 2.83 ± 0.87 (1.67–3.95) | 2.56 ± 0.8* (1.05–3.95) |
Demographics and cognitive/functional profile of BHR-IDEAS participants. For continuous variables, mean ± SD (range) is shown. For categorical variables, number of participants (% of total in diagnostic group) is shown.
*
p<0.05 versus total MCI group using Mann-Whitney for continuous variables or chi squared test of proportions for categorical variables.