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. 2020 Oct 9;183:114278. doi: 10.1016/j.bcp.2020.114278

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Fig. 7 — The Bohr Effect. The action of the Cl^–/HCO₃^– exchanger AE1 and cytosolic carbonic anhydrase II (CAII) promote O₂ release in systemic capillaries (panel A) and CO₂ release in pulmonary capillaries because of the pH-dependence of the affinity of hemoglobin for O₂ (the Bohr effect).