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. 2020 Sep 11:1–8. doi: 10.1080/13813455.2020.1817944

Table 1.

Potential targets of matrine.

MolId Target Symbol Relevance score
GeneCards CTD
MOL005944 Transcription factor p65 RELA ns 25.61
MOL005944 72 kDa type IV collagenase MMP2 ns 14.36
MOL005944 Tumor necrosis factor TNF 53.73 29.61
MOL005944 Interleukin-6 IL6 49.73 23.63
MOL005944 Caspase-3 CASP3 27.96 25.37
MOL005944 Myc proto-oncogene protein MYC ns 16.87
MOL005944 Intercellular adhesion molecule 1 ICAM1 ns 16.65
MOL005944 Heparanase HPSE ns 2.79
MOL005944 Immediate early response 3-interacting protein 1 IER3IP1 ns 2.51
MOL005944 CD44 antigen CD44 ns 1.68

The two columns on the right of the table indicate the correlation between the COVID-19 and the targets in different databases. The “ns” means no relevant data. The “Relevance score” indicates how relevant the disease is to the target.