TABLE 2.
Psychophysics visual test studies in ALS patients.
| Study and year of publication | Alterations in visual functions in ALS |
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| VEP | ERG | VA | VF | CS | |
| Matheson et al., 1986 | Abnormal latencies between eyes | – | – | – | – |
| Ghezzi et al., 1989 | WNL | – | – | – | – |
| Münte et al., 1998 | P300 delayed and attenuated | P1 absent | – | – | – |
| González Díaz et al., 2004 | P100 latency prolongation | WNL | – | – | – |
| Fawzi et al., 2014 | – | – | – | – | ↓CS |
| Volpe et al., 2015 | – | – | No changes high contrast VA | – | No changes |
| Moss et al., 2016 | – | – | ↓High contrast and low contrast VA | – | – |
| Liu et al., 2018 | – | – | – | MS↓ and ↑sLV | – |
| Rojas et al., 2019 | – | – | No changes high contrast VA | ↓ reliability index (↑fixation losses, ↑false positives and negatives) | – |
ALS, amyotrophic lateral sclerosis; VEP, visual evoked potentials; ERG, electroretinogram; VA, visual acuity; VF, visual field; CS, contrast sensitivity; WNL, within normal limits; MS, mean sensibility; sLV, square of loss variance.