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Lowest energy binding affinity of Piperine and few of the currently used drugs for SARS-CoV-2 as obtained from molecular docking study.
| Molecule | Binding affinity (kcal/mol) |
|
|---|---|---|
| RBD Spro | Mpro | |
| Piperine | –6.4 | –7.3 |
| Chloroquine | –5.0 | –4.9 |
| Favipiravir | –5.3 | –5.6 |
| Hydroxychloroquine | –4.8 | –6.0 |
| Oseltamivir | –5.1 | –5.5 |
| Remdesivir | –6.1 | –7.2 |
| Ribavirin | –5.6 | –6.1 |
