Table 4.
A list of Interacting residues of docked vaccine-TLR-3 complex.
| Vaccine model | TLR-3 receptor | Distance | Buried SASA | Vaccine model | TLR-3 receptor | Distance | Buried SASA |
|---|---|---|---|---|---|---|---|
| B:13:Leu | A:287:AsnA:288:Val | 2.1 A3.5 A | 60.70% | B:572:Thr | A:278:Met | 3.9 A | 76.10% |
| B:38:Val | A:247:Asn | 3.0 A | 8.20% | B:574:Arg | A:227:PheA:229:AsnA:254:SerA:203:Glu | 1.5 A1.8 A2.7 A3.9 A | 89.30% |
| B:39:Ser | A:247:Asn | 3.2 A | 24.80% | B:582:Cys | A:39:His | 3.9 A | 28.10% |
| B:40:Ser | A:273:TrpA:247:AsnA:272:Lys | 2.7 A3.0 A3.7 A | 73.80% | B:594:Val | A:283:Tyr | 3.4 A | 59.30% |
| B:41:Gly | A:272:Lys | 3.5 A | 0.10% | B:595:Lys | A:230:AsnA:229:AsnA:256:SerA:257:Asn | 2.0 A3.3 A3.5 A3.9 A | 82.70% |
| B:42:Gly | A:272:Lys | 1.5 A | 56.70% | B:596:Leu | A:206:SerA:230:AsnA:180:Asn | 2.5 A3.2 A3.4 A | 59.50% |
| B:43:Gln | A:272:Lys | 2.9 A | 15.90% | B:606:Leu | A:60:His | 2.9 A | 71.30% |
| B:44:Cys | A:273:Trp | 3.5 A | 57.60% | B:608:Ala | A:108:His | 3.0 A | 21.90% |
| B:45:Leu | A:296:TrpA:269:Leu | 3.1 A3.4 A | 52.50% | B:612:Ala | A:156:His | 3.0 A | 69.00% |
| B:46:Tyr | A:269:Leu | 3.5 A | 1.50% | B:613:Tyr | A:180:AsnA:156:His | 3.0 A3.5 A | 77.30% |
| B:47:Ser | A:269:Leu | 3.3 A | 59.50% | B:614:Asn | A:156:HisA:180:AsnA:179:SerA:203:Glu | 2.7 A3.0 A3.4 A4.0 A | 100.00% |
| B:48:Ala | A:273:Trp | 2.6 A | 97.90% | B:615:Ile | A:203:GluA:201:LysA:227:Phe | 1.4 A2.6 A3.8 A | 94.80% |
| B:49:Cys | A:243:Leu | 3.5 A | 31.90% | B:617:Asn | A:177:LeuA:153:Asp | 3.3 A3.5 A | 53.90% |
| B:50:Pro | A:243:LeuA:246:Ala | 1.8 A3.4 A | 94.20% | B:619:Ser | A:131:MetA:107:GlnA:156:His | 3.3 A3.5 A3.9 A | 99.00% |
| B:51:Ile | A:243:LeuA:244:Glu | 3.6 A3.9 A | 41.10% | B:620:Leu | A:84:PheA:108:HisA:107:Gln | 1.1 A3.1 A3.8 A | 87.80% |
| B:52:Phe | A:244:GluA:218:HisA:243:LeuA:215:Gly | 2.7 A2.8 A3.6 A3.8 A | 98.30% | B:621:Val | A:84:PheA:60:HisA:107:Gln | 2.2 A2.3 A3.4 A | 55.90% |
| B:55:Ile | A:215:Gly | 3.9 A | 49.50% | B:622:Lys | A:60:His | 3.6 A | 0.00% |
| B:59:Cys | A:273:Trp | 3.7 A | 59.00% | B:623:Ala | A:39:HisA:60:His | 1.6 A1.6 A | 99.60% |
| B:524:Leu | A:325:Arg | 3.5 A | 32.50% | B:624:Ala | A:39:His | 1.7 A | 59.90% |
| B:550:Tyr | A:358:GluA:382:Lys | 1.7 A2.1 A | 64.20% | B:625:Tyr | A:41:LysA:39:His | 1.9 A3.2 A | 41.90% |
| B:563:Ala | A:380:Asn | 3.6 A | 66.40% | B:626:Ser | A:41:Lys | 2.9 A | 5.90% |
| B:564:Ala | A:356:Cys | 3.9 A | 85.50% | B:627:Phe | A:41:Lys | 3.6 A | 0.00% |
| B:566:Gly | A:325:ArgA:358:Glu | 2.9 A4.0 A | 90.00% | B:654:Ile | A:41:LysA:62:Gln | 0.9 A3.0 A | 68.40% |
| B:567:Thr | A:325:Arg | 4.0 A | 0.00% | B:655:Ala | A:40:LeuA:41:Lys | 2.5 A2.5 A | 92.90% |
| B:568:His | A:302:TyrA:301:Glu | 2.2 A2.3 A | 50.50% | B:664:Phe | A:27:Lys | 1.4 A | 12.60% |
| B:569:Trp | A:302:Tyr | 2.7 A | 22.90% | B:665:Phe | A:27:LysA:26:ThrA:28:Cys | 1.3 A2.6 A2.7 A | 77.60% |
| B:570:Phe | A:302:Tyr | 3.2 A | 27.10% | B:667:Met | A:26:Thr | 3.1 A | 67.00% |