Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 25;10:577636. doi: 10.3389/fonc.2020.577636

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Zhou, Gong, Lin, Wang, Li, Wang, Ding and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The comprehensive mechanism of SRSF3 functions as an oncogene by regulating multiple splicing targets in cancer cells. On the one hand, SRSF3 can enhance cell proliferation, migration, invasion, metastasis, transformation, drug resistance, tumorigenesis, and energy metabolism. On the other hand, SRSF3 can inhibit cell cycle arrest, apoptosis, cellular senescence, and autophagy. SRSF3 is also involved in immunotherapy resistance, tumor microenvironment, cell homeostasis, and maintenance of HPV-related cancer.