TABLE 3.
Features of PAIs found in the different DEC pathotypes.
| Name | Alternative names | Insertion site | Size (kb) | Main determinants encoded within the PAIa | DECb |
| LEE PAI | selC, pheV, pheU | 35.6-111 | T3aSS apparatus, Intimin, Tir, Ter system*, LifA* | EPEC, tEHEC | |
| PAI pic/set | SHI-1, She, PAI IICFT073 | pheV | 46.6-71.6 | Pic, ShET1 | EAEC, EIEC, EHEC, EPEC, DAEC |
| LAA PAI | pheV, selC, ileX, serX, thrW | 86.3 | SisA, Hes, IhA, LesP, PagC, SlhA, Ag43 | aEHEC, EPEC, EAEC | |
| PAI iuc/iut | SHI-2, SHI-3 | selC, pheU, pheV | 21-30 | Aerobactin, ShiA*, ShiD* | EIEC |
| PAI tia | selC | 46 | Tia, LeoA | ETEC, EPEC, EHEC | |
| PAI tibA | – | 21.6 | TibA | ETEC | |
| SE PAI | pheV | 8 | SubAB, Tia, ShiA | aEHEC | |
| SHI-O PAI | proAB, thrW, argW | 4.6 | GtrABV | EIEC, EAEC | |
| SRL PAI | serX, serW, orf58 | 66 | StrepR, AmpR, CmR, TetR, FecABCDE-I-R, AspR-DcuA | EIEC, EHEC | |
| PAI espC | orf360, ssrA | 15.2 | EspC, VirA | EPEC, EHEC | |
| PAI sit | aspS, yecN | 10-34 | SitABCD | EIEC, | |
| HPI | asnT, asnV | 40 | Ybt | EAEC, EIEC, EPEC, ETEC, EHEC | |
| PAI IIAL862 | pheV | 61 | Afa/Dr, DeoK | DEC |
aMain virulence or niche factors. ∗Molecular determinants that can be absent from some version of the PAI. bDEC pathotypes where the PAI can be present. EPEC, enteropathogenic E. coli, EHEC, enterohemorrhagic E. coli, tEHEC, typical EHEC (LEE positive); aEHEC, atypical EHEC (LEE negative); ETEC, enterotoxigenic E. coli; EAEC, enteroaggregative E. coli; EIEC, enteroinvasive E. coli (including Shigella); DAEC, diffusely adherent E. coli; DEC, diarrheagenic E. coli (pathotype undefined among the above).