Table 3.

Statistical Analysis of Untreated Control Paradigms Across Experiments 1, 2, and 3

Ocular Parameter	Test	Age Matched	Contralateral	Age Matched vs Contralateral
Axial length	ANOVA	F(2, 28) = 0.663, P = 0.524	F(2, 88) = 0.146, P = 0.932	—
	MANOVA	—	—	Wilks’ λ = 0.463, F(1, 59) = 1.221, P = 0.359
Refraction	ANOVA	F(2, 28) = 1.353, P = 0.277	F(2, 88) = 2.155, P = 0.121	—
	MANOVA	—	—	Wilks’ λ = 0.532, F(1, 59) = 1.763, P = 0.284

ANOVAs were undertaken to compare whether similar ocular biometry was seen in age-matched untreated control eyes across all three experimental groups. The same analysis was undertaken for contralateral control values across experiments. To expand on this, MANOVAs were undertaken to compare whether the ocular biometry observed between the two control groups (age-matched untreated controls and contralateral controls) were similar across all three experiments.