Table 2.
Summary of Findings for Quantitative Analysis and GRADE Quality of Evidence Assessment
| GRADE Scorea | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Intervention | Outcome | No. of Studies (RCT/NRS) | Effect Size (95% CI) | I 2 | Risk of Bias | Inconsistency | Indirectness | Imprecision | Other Considerations | Quality |
| Self-testing compared with facility-based testing | Test uptake | 9 (9/0) | 2.59 [1.06–6.29] |
99% | Serious | Serious | Not serious | Not serious | None | Moderate |
| STI self-sampling compared with facility-based testing | Test uptake | 7 (7/0) | 1.74 [0.97–3.12] |
95% | Not serious | Serious | Not serious | Not serious | None | Moderate |
| Digital intervention compared with facility-based testing | STI test uptake | 3 (2/1) | 3.50 [1.35–9.08] |
99% | Serious | Not serious | Not serious | Serious | None | Low |
Abbreviations: NRS, nonrandomized studies; RCT, randomized controlled trial; STI, sexually transmitted infection.
aFor complete GRADE tables and justification for downgrading quality of evidence, see the Supplementary Data.