Table 1.
GC-FP detection ratio data for serum and dried blood spot samples with verified infection status. ELISA and Luminex MIA data are shown for serum samples tested with these assays. Samples scored positive (GC-FP detection ratio above the ROC threshold) are denoted by bold text. The Nuc diagnostic score and machine learning (ML) score are shown for dried blood spot samples.
| Serum Samples | ||||||
| Sample ID | S1 | S1S2 | Nuc | Nuc-ELISA (score/A450) | Nuc-MIA (score/MFI) | Notes |
| 2_1 | 0.67 | 1.55 | 0.81 | neg/0.054 | n/a | no known exposure |
| 2_2 | 0.61 | 0.94 | 0.72 | neg/0.027 | n/a | no known exposure |
| 2_3 | 0.79 | 0.77 | 0.74 | neg/0.013 | n/a | no known exposure |
| 2_4 | 0.79 | 0.77 | 0.67 | neg/0.046 | n/a | no known exposure |
| 2_5 | 0.52 | 1.33 | 0.77 | neg/0.032 | n/a | no known exposure |
| 2_6 | 0.61 | 1.60 | 0.70 | neg/0.031 | n/a | no known exposure |
| 2_7 | 0.62 | 1.37 | 0.71 | neg/0.037 | n/a | no known exposure |
| DIL0526-26 | 0.42 | 0.92 | 0.59 | n/a | neg/259 | 2009 pre-COVID |
| DIL0526-27 | 0.41 | 1.20 | 0.52 | n/a | neg/421 | 2009 pre-COVID |
| DIL0526-28 | 0.45 | 1.23 | 0.65 | n/a | neg/1563 | 2009 pre-COVID |
| DIL0526-29 | 0.48 | 2.03 | 0.59 | n/a | neg/238 | 2009 pre-COVID |
| DIL0526-30 | 0.37 | 1.36 | 0.43 | n/a | neg/719 | 2009 pre-COVID |
| 1_1 | 1.20 | 3.31 | 1.16 | pos/0.123 | n/a | Positive by RT-PCR |
| 1_2 | 3.69 | 5.65 | 1.09 | pos/0.178 | n/a | Positive by RT-PCR |
| 1_3 | 7.65 | 11.73 | 4.80 | pos/1.577 | n/a | Positive by RT-PCR |
| 1_4 | 1.49 | 5.41 | 0.99 | neg/0.043 | n/a | Positive by RT-PCR |
| 1_5 | 1.56 | 4.59 | 2.23 | pos/0.491 | n/a | Positive by RT-PCR |
| DIL0526-3 | 7.81 | 9.44 | 3.89 | n/a | pos/45,543 | Positive by RT-PCR |
| DIL0526-5 | 8.00 | 7.61 | 4.55 | n/a | pos/47,301 | Positive by RT-PCR |
| DIL0526-8 | 3.45 | 6.23 | 3.00 | n/a | pos/39,255 | Positive by RT-PCR |
| DIL0526-13 | 2.35 | 4.06 | 1.11 | n/a | pos/11,577 | Positive by RT-PCR |
| DIL0526-18 | 1.12 | 6.31 | 2.60 | n/a | pos/34,715 | Positive by RT-PCR |
| DIL0526-21 | 0.95 | 4.16 | 1.11 | n/a | pos/28,806 | Positive by RT-PCR |
| Dried Blood Spot Samples (Verified Infection Status) | ||||||
| Sample ID | S1 | S1S2 | Nuc | Nuc Score | ML Score | Notes |
| COV_5 | 0.54 | 0.73 | 0.70 | neg | neg | Negative by RT-PCR |
| COV_6 | 0.72 | 1.11 | 0.70 | neg | neg | Negative by RT-PCR |
| COV_7 | 0.06 | 0.08 | 0.06 | neg | neg | Negative by RT-PCR |
| COV_9 | 0.85 | 1.00 | 0.95 | neg | neg | Negative by RT-PCR |
| COV_14 | 0.46 | 0.52 | 0.48 | neg | neg | Negative by RT-PCR |
| COV_16 | 0.77 | 0.93 | 0.84 | neg | neg | Negative by RT-PCR |
| COV_18 | 0.62 | 0.76 | 0.74 | neg | neg | Negative by RT-PCR |
| COV_12 | 0.76 | 0.87 | 0.85 | neg | neg | IgG and IgM negative |
| COV_2 | 0.65 | 0.80 | 0.72 | neg | neg | Positive by RT-PCR |
| COV_3 | 1.59 | 1.13 | 5.63 | pos | pos | Positive by RT-PCR |
| COV_13 | 0.53 | 0.67 | 0.65 | neg | neg | Positive by RT-PCR |
| COV_17 | 0.94 | 1.11 | 1.01 | pos | pos | Positive by RT-PCR |
| COV_28 | 0.80 | 1.37 | 3.53 | pos | pos | Positive by RT-PCR |
| COV_29 | 1.70 | 1.51 | 1.57 | pos | pos | Positive by RT-PCR |
| COV_40 | 1.15 | 1.50 | 2.37 | pos | pos | Positive by RT-PCR |
| COV_41 | 0.86 | 1.06 | 1.02 | pos | pos | Positive by RT-PCR |
| COV_43 | 0.52 | 0.70 | 1.19 | pos | neg | Positive by RT-PCR |
| COV_44 | 3.13 | 2.85 | 8.92 | pos | pos | Positive by RT-PCR |
| NYC_1 | 1.16 | 2.09 | 1.29 | pos | pos | Positive by RT-PCR |
| NYC_5 | 0.95 | 2.09 | 1.90 | pos | pos | Positive by RT-PCR |
| COV_19 | 0.89 | 1.52 | 1.37 | pos | pos | IgG pos., no PCR test |
| COV_38 | 0.86 | 1.33 | 1.30 | pos | pos | IgG pos., no PCR test |
| COV_24 | 0.84 | 1.16 | 1.01 | pos | pos | IgM pos., no PCR test |