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. 2020 Sep 25;10:557638. doi: 10.3389/fonc.2020.557638

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Copyright © 2020 Gao, Chen, Vafaei and Zhong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The Utilization of TICS for Chemosensitivity Prediction. These figures refer to the TCGA (n = 88) and ICGC-PACA-CA cohorts (n = 106). (A) Heatmap of the immune cells and immune related genes between the patients with status CR and non-CR after chemotherapy. (B,C) Survival analysis for patients with and without chemotherapy in TCGA and ICGC cohorts, respectively. (D,E) Bar and box plot for the relationship between TICS and chemosensitivity in the TCGA cohort. Complete Response (CR), Partial Response (PR), Stable Disease (SD) and Progressive Disease (PD). (F,G) Bar and box plot for the relationship between TICS and chemosensitivity in the ICGC-PACA-CA cohort. (H,I) ROC analysis of TICS and the combination with other immune-related genes for predicting the complete response status in both cohorts.