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. 2020 Apr 22;158(4):1680–1688. doi: 10.1016/j.chest.2020.03.070

Table 2.

Multivariable Linear Regression Model to Test Independent Association, and Interaction, Between Smoking Rate and Sleep Duration on 6-Min Walk Test Distance Covereda

Study Variable Slope Estimate 95% CI P Value
Smoking rate –5.37 10.37 to –0.38 .04
Sleep duration –0.14 –0.33 to 0.06 .18
FVC 0.32 –0.01 to 0.64 .05
Heart rate at 1 min of recovery 1.02 0.22 to 1.82 .01
Oxygen saturation 6.76 1.90 to 11.62 .01
Apnea-hypopnea index –1.61 –3.79 to 1.48 .39
Smoking rate × sleep duration 0.02 0.00 to 0.03 .04
a

Model adjusted for age, biological sex, educational attainment (at least 8 y of schooling or not), BMI, Center for Epidemiologic Studies-Depression Scale, use of antihypertensives, use of nodal blockers, use of statins, use of COPD medication (long-acting muscarinic antagonist, long-acting β-agonist, or inhaled corticosteroid), use of diabetes medication, evidence of diabetes, oxygen saturation, FVC, apnea-hypopnea index, and 1-min resting heart rate.