Table 2.
Multivariable Linear Regression Model to Test Independent Association, and Interaction, Between Smoking Rate and Sleep Duration on 6-Min Walk Test Distance Covereda
| Study Variable | Slope Estimate | 95% CI | P Value |
|---|---|---|---|
| Smoking rate | –5.37 | 10.37 to –0.38 | .04 |
| Sleep duration | –0.14 | –0.33 to 0.06 | .18 |
| FVC | 0.32 | –0.01 to 0.64 | .05 |
| Heart rate at 1 min of recovery | 1.02 | 0.22 to 1.82 | .01 |
| Oxygen saturation | 6.76 | 1.90 to 11.62 | .01 |
| Apnea-hypopnea index | –1.61 | –3.79 to 1.48 | .39 |
| Smoking rate × sleep duration | 0.02 | 0.00 to 0.03 | .04 |
Model adjusted for age, biological sex, educational attainment (at least 8 y of schooling or not), BMI, Center for Epidemiologic Studies-Depression Scale, use of antihypertensives, use of nodal blockers, use of statins, use of COPD medication (long-acting muscarinic antagonist, long-acting β-agonist, or inhaled corticosteroid), use of diabetes medication, evidence of diabetes, oxygen saturation, FVC, apnea-hypopnea index, and 1-min resting heart rate.