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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Strahlenther Onkol. 2020 Aug 21;196(10):900–912. doi: 10.1007/s00066-020-01679-9

Figure 5. Adapted workflow for comparisons of pre- and post-treatment mpMRIs in prostate cancer radiotherapy clinical trials at the University of Miami.

Figure 5.

Six image fusions are carried out, indicated on the graph above. (1) Using prostate anatomical matching, the diagnostic MRI is fused with the planning MRI; (2) The planning MRI is fused to the planning CT, using fiducial matching; (3) Using (1) and (2), the diagnostic MRI is fused to the planning MR for target volume contouring; (4–6) The post-RT MRIs (at 3 and 9 mo) and the one before the endpoint biopsy (2.0 – 2.5 yr after completion of all therapy) is fused with both the pre-RT planning and diagnostic MRI.