Table 4.
Neuronal Density, Total Neuron Number, TH Immunohistochemistry, and Histology of the SNpc in SIDS Cases Divided in Groups According to Age.
| Groups | Age (in weeks) | Number of cases | Neuron density |
Neuron number |
TH-immunopositive neuron number |
Histology |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| Range | M | Range | M | Range | M | Normal | Hypoplasia | |||
| I | 4–8 | 5 | 8–20 | 16.8 | 89–320 | 142 | 17–180 | 109.0 | 2 | 2 |
| II | 9–12 | 5 | 13–29 | 17 | 83–104 | 96 | 16–78 | 29.6 | 1 | 4 |
| III | 13–16 | 7 | 5–20 | 13.6 | 98–298 | 144.3 | 17–55 | 30.4 | / | 7 |
| IV | 17–20 | 3 | 23–88 | 58.3 | 70–99 | 85.6 | 9–18 | 14.0 | / | 3 |
| V | 21–24 | 3 | 59–89 | 74.3 | 75–298 | 194.3 | 9–27 | 16.6 | 1 | 2 |
| VI | 25–30 | 3 | 88–100 | 95.6 | 189–316 | 251.6 | 15–82 | 38.3 | 3 | / |
Note. M = mean; TH = tyrosine hydroxylase.