Table 1.
Baseline Characteristics of study subjects with and without Diabetes or Metabolic Syndrome by Study Group: Multi-Ethnic Study of Atherosclerosis
| Characteristic | MetS without DM (N=1596) | DM (N=838) | Neither DM nor MetS (N=3983) |
|---|---|---|---|
| Mean ± SD or N (%) | |||
| Age (years)* | 63.1 ± 10.0 | 64.7 ± 9.6 | 61.2 ± 10.3 |
| Male | 656 (41.1 %) | 438 (52.3 %) | 1957 (49.1 %) |
| Female | 940 (58.9 %) | 400 (47.7 %) | 2026 (50.1 %) |
| White | 644 (25.9 %) | 157 (6.3 %) | 1683 (67.8 %) |
| Black | 150 (19.4 %) | 102 (13.2 %) | 522 (67.4 %) |
| Hispanic | 407 (23.0 %) | 325 (18.4 %) | 1034 (58.6 %) |
| Chinese American | 395 (28.4 %) | 254 (18.2 %) | 744 (53.4 %) |
| Systolic BP (mm Hg)* | 133.6 ± 20.6 | 133.0 ± 22.2 | 122.2 ± 20.6 |
| BP Medication* | 760 (47.6 %) | 472 (56.3 %) | 862 (21.6 %) |
| BMI (kg/m2)* | 30.8 ± 5.1 | 30.3 ± 5.8 | 26.7 ± 4.9 |
| Cholesterol (mg/dL)* | 195.8 ± 35.5 | 188.0 ± 37.5 | 193.8 ± 33.6 |
| Triglycerides (mg/dL)* | 172.5 ± 68.6 | 144.4 ± 73.6 | 102.9 ± 49.0 |
| Smoker | 790 (49.6 %) | 422 (50.4 %) | 1954 (49.2 %) |
| Family History of CHD† | 688 (43.1 %) | 320 (38.2 %) | 1549 (38.9 %) |
| Statin Use* | 259 (16.2 %) | 208 (24.8 %) | 470 (11.8 %) |
| HDL-C (mg/dl)* | 43.2 ± 10.2 | 46.8 ± 13.2 | 55.2 ± 15.1 |
| HDL-P (μmol/l)* | 32.6 ± 6.4 | 32.7 ± 6.3 | 34.8 ± 6.7 |
| LDL-C (mg/dl)* | 118.1s 32.3 | 112.3 ± 33.4 | 118.0 ± 30.5 |
| LDL-P (μmol/l)* | 1354.3 ± 354.9 | 1264.8 ± 344.9 | 1199.2 ± 313.3 |
*
p<0.001,
†
p<0.01.
Denotes statistical significance between the three study groups (DM, MetS without DM, and Neither Disease)
Abbreviations: DM, Diabetes; MetS, Metabolic Syndrome; BP, Blood Pressure; BMI, Body Mass Index; CHD, Coronary Heart Disease; HDL-C, high-density lipoprotein cholesterol; HDL-P, high-density lipoprotein particle; LDL-C, low-density lipoprotein cholesterol; LDL-P, low-density lipoprotein particle.