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. 2020 Oct 8;18:381. doi: 10.1186/s12967-020-02561-z

Fig. 7.

Fig. 7

GO enrichment analysis for the light-yellow module. a The upset plot showing overlap of genes across enriched biological pathways; b dot plot showing the ordered enrichment biological pathways; c Enriched terms were organized into a network with edges connecting overlapping gene sets. In this way, mutually overlapping gene sets are tend to cluster together, making it easy to identify functional modules; and d The category netplot depicts the linkages of genes and GO terms as a network, which is helpful to see which genes are involved in enriched pathways and genes that may belong to multiple annotation categories. The most important biological pathways in the module involves the translation and catabolic processes, including nucleobase-containing compound catabolic process, heterocycle catabolic process and cellular nitrogen compound catabolic process