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EOAD family carrying p.I2012T mutation in LRRK2 gene. Note: (A) the pedigree of the EOAD family carrying p.I2012T in LRRK2 gene, the black arrow shows the proband. (B) sanger sequencing diagram of p.I2012T mutation, and the black arrow shows the mutated site. (C) Brain MRI of the II:3 case showed mild to moderate atrophy in the bilateral hippocampus, temporal and parietal areas.
