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Summary of adverse events
| Adverse events | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|
| Fatigue | 1 | 1 | ||
| Oral ulcer | 1 | |||
| Leukocyte decrease | 1 | |||
| Blood bilirubin increase | 1 | |||
| Thromboembolic events | 1 | |||
| Alanine aminotransferase increased | 1 | 1 | ||
| Headache | 2 | |||
| Palpitation | 2 | |||
| Hyperglycemia | 1 | |||
| Anorexia | 1 | |||
| Backache | 1 |
