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. 2020 Sep 25;11(22):6748–6759. doi: 10.7150/jca.48535

Figure 2.

Figure 2

YAP-knockdown altered trastuzumab (Traz) treatment effects and p73 expression in BT474-TS cells. (A) YAP-knockdown increased viability of BT474-TS cells after trastuzumab treatment. (B) YAP-knockdown altered apoptosis, measured by flow cytometry, after treatment in BT474-TS cells. (C) Expression of apoptotic proteins was examined by western blotting. (D) p73 protein expression was detected by western blotting in different cancer cells. Data represent the mean ± standard deviation (SD) of three independent experiments. *p < 0.05, **p < 0.01, and *** p < 0.001.