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. 2020 Sep 25;11(22):6737–6747. doi: 10.7150/jca.48132

Figure 2.

Figure 2

High expression of UPK1A predicted poor clinical outcome of patients with HCC. (A) Expression of UPK1A was evaluated in 17-Patient cohort by qRT-PCR. (B) Left panel, analysis of UPK1A expression in HCC patients from TCGA datasets (n=358). Right panel, Re-analysis of UPK1A expression level in 49 paired HCC samples and adjacent non-tumor samples from TCGA datasets (n=49). (C) Expression of UPK1A in HCC patients from GSE22058, GSE36376, and ICGC-LIRI-JP. (D) UPK1A expression level in healthy liver, cirrhotic liver, and HCC tissues. (E) UPK1A expression level in non-tumor tissue and different stage of HCC. (F) GSEA analysis suggested high UPK1A expression was association with gene signatures of poor liver cancer survival. (G) Kaplan-Meier survival analysis of overall survival of HCC patients from ICGC-LIRI-JP database. (H) Kaplan-Meier survival analysis of overall survival of HCC patients from TCGA datasets using Kaplan Meier Plotter online program.