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. 2020 Sep 19;16(15):2974–2988. doi: 10.7150/ijbs.50186

Figure 1.

Figure 1

The identification and verification of aberrantly expressed genes in SIMD heart tissues. (A) Heat map of differentially expressed genes identified in SIMD heart tissues. Total RNA samples from three independent heart tissues of control mice and SIMD mice were used for microarray analysis. The aberrantly expressed genes that showed converse expression patterns between controls and SIMD mice were selected and presented in a heat map. (B-G) RT-qPCR results. Total RNA samples isolated from heart tissues of controls (n=24) and SIMD mice (n=24) were used to detect the mRNA levels of three overexpressed genes, IL1B (B), CUL4A (C), and S100A8 (D), and three downregulated genes, PLD2 (E), ZFP91 (F), and BIRC5 (G). * P < 0.05, ** P < 0.01 and *** P < 0.001.