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. 2020 Aug 25;16(15):2788–2802. doi: 10.7150/ijbs.48204

Figure 5.

Figure 5

UCP2 deletion increased the levels of mitochondrial fission-related proteins in hyperglycemic mice after ischemia/reperfusion. Detections of mitochondrial fission-related proteins by immunohistochemistry and Western blotting (n=6, per group). (A, B) Representative photomicrographs for Fis1 and Drp1. Scale bar=50 μm. (C, D) Quantification of Fis1 and Drp1 immunointensity. E: Representative Western blots for Fis1 and Drp1. (F, G) Semi-quantification of Fis1 and Drp1 protein bands. Data are shown as mean ± SD. For values in F and G, the values in WT+NG sham group were converted to 100 and percent changes were presented for other groups relative to the WT+NG sham. Δp<0.05 vs. respective sham-operated controls, #p<0.05 vs. normoglycemic and *p<0.05 vs. WT counterpart at an identical reperfusion stage.