Table 1.
Summary of group and subgroups
| Groups | Processing | TTC | Histo | WB | TEM |
|---|---|---|---|---|---|
| WT | |||||
| NG | |||||
| Sham | Sham-operated | 4 | 10 | 4 | 4 |
| 6h I/R | MCAO + reperfusion 6h | 0 | 6 | 6 | 4 |
| 24h I/R | MCAO + reperfusion 24h | 4 | 10 | 6 | 0 |
| 72h I/R | MCAO + reperfusion 72h | 0 | 6 | 6 | 0 |
| HG | |||||
| Sham | Sham-operated | 0 | 10 | 4 | 4 |
| 6h I/R | MCAO + reperfusion 6h | 0 | 6 | 6 | 4 |
| 24h I/R | MCAO + reperfusion 24h | 4 | 10 | 6 | 0 |
| 72h I/R | MCAO + reperfusion 72h | 0 | 6 | 6 | 0 |
| UCP2-/- | |||||
| NG | |||||
| Sham | Sham-operated | 5 | 10 | 4 | 4 |
| 6h I/R | MCAO + reperfusion 6h | 0 | 6 | 6 | 4 |
| 24h I/R | MCAO + reperfusion 24h | 5 | 10 | 6 | 0 |
| 72h I/R | MCAO + reperfusion 72h | 0 | 6 | 6 | 0 |
| HG | |||||
| Sham | Sham-operated | 0 | 10 | 4 | 4 |
| 6h I/R | MCAO + reperfusion 6h | 0 | 6 | 6 | 4 |
| 24h I/R | MCAO + reperfusion 24h | 5 | 10 | 6 | 0 |
| 72h I/R | MCAO + reperfusion 72h | 0 | 6 | 6 | 0 |
WT: Wildtype mice; UCP2-/-: knock out UCP2 mice; NG: normoglycemia; HG: hyperglycemia; 6h I/R, 24h I/R and 72h I/R: MCAO and reperfusion 6h, 24h, and 72h. MCAO: middle cerebral artery occlusion; TTC: 2,3,5-triphenyltetrazolium chloride; Histo: histology; WB: Western blot; TEM: transmission electron microscopy.