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. 2020 Sep 16;16(15):2938–2950. doi: 10.7150/ijbs.47051

Figure 1.

Figure 1

Lnc-MCEI was up-regulated in the ESCC tissues and tissues with non-pathological complete response (non-pCR). A. Flow diagram of data analysis based on the published microarray data (GSE89102) with R package limma. BH-corrected p value < 0.01 was considered to be statistically significant. B. A heat map demonstrated the significantly differential expressed genes (DEGs). The bottom bar denotes the sample types that the red indicates tumor tissues and the blue indicates normal tissues. C. Lnc-MCEI was one of most significantly up-regulated genes in ESCC tissues among the DEGs. D. Significantly up-regulated lnc-MCEI in tissues with non-pathological complete response (non-pCR) compared to pathological complete response (pCR). E. The significantly higher lnc-MCEI expression in tumor tissues compared with the normal tissues according to data from The Cancer Genome Atlas (TCGA) RNA-Seq database. F. Increased expression of lnc-MCEI was significantly associated with poor patient survival (P = 0.17). G. The significantly up-regulated lnc-MCEI in ESCC tissues were observed compared to the normal controls. N = 50. H. Lnc-MCEI expression was significantly higher in ESCC tissues than the matched normal tissues. N = 50. I. Lnc-MCEI was significantly up-regulated in ESCC cell lines compared to the human esophageal epithelial cell line (Het-1A). *P < 0.05.