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. 2020 Sep 25;11:556729. doi: 10.3389/fmicb.2020.556729

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Copyright © 2020 Barnett and Gibson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Glyphosate residues present on food may cause intestinal dysbiosis. (A) Glyphosate exhibits its herbicidal action through inhibition of the shikimate pathway enzyme EPSPS. Class I EPSPS are sensitive to the effects of glyphosate and are found in all plants and bacteria. However, glyphosate resistant EPSPS (Class II) appear to be more prevalent in opportunistic pathogens and may contribute to dysbiosis. (B) Summary of the alterations in microbial composition reported in the literature when administering either glyphosate or glyphosate-based herbicides.