Table 1.
Demographic and Clinical Characteristics by Intervention group (n = 48).
| Characteristics | Chamomile gel n = 24 | Urea cream n = 24 | P-value* |
|---|---|---|---|
| Age, in years, Mean (Standard deviation) Median (min, max) |
56 (16) 59 (19, 83) |
59 (13) 60 (26, 79) |
.57 |
| Sex, n (% male) | 16 (67) | 17 (71) | 1.00 |
| Tumor site, n (%) | |||
| Nasal cavity | 1 (4) | 0 (0) | .92 |
| Oral cavity | 9 (38) | 10 (42) | |
| Larynx | 6 (25) | 7 (29) | |
| Pharynx (nasopharynx, oropharynx and, hypopharynx) | 7 (29) | 5 (21) | |
| Other sites | 1 (4) | 2 (8) | |
| Diabetes, n (% yes) | 5 (21) | 3 (12) | .70 |
| Smoking, n (%) | |||
| Current or former smoker | 19 (79) | 19 (79) | 1.00 |
| Never smoked | 5 (21) | 5 (21) | |
| Alcohol consumption, n (%) | |||
| Current or former drinker | 16 (67) | 19 (79) | .52 |
| Never drank | 8 (33) | 5 (21) | |
| Current treatment, n (%) | |||
| Radical radiotherapy | 8 (33) | 9 (38) | 1.00 |
| Chemoradiotherapy | 16 (67) | 15 (62) | |
| Radiotherapy type, n (%) | |||
| 2DRT | 2 (8) | 1 (4) | 1.00 |
| 3D-CRT | 22 (92) | 23 (96) | |
| Total dose (Gy), Median (min, max) | 70 (36, 70) | 70 (30, 70) | .37 |
| Fractioned sose (Gy), n (%) | |||
| 1.80 | 7 (29) | 6 (25) | 1.00 |
| 2.00 | 16 (67) | 17 (71) | |
| 2.25 | 0 (0) | 1 (4) | |
| 2.50 | 1 (4) | 0 (0) | |
| Fractions, Median (min, max) | 35 (20, 39) | 35 (15, 39) | .45 |
*
P-value from Student t-test for equality of means of age, from Mann–Whitney test for equality of distribution of total dose and fractions, and from Fisher Exact test for all others.