Table 3.

Summary statistics for read coverage distribution per variant across approaches

Approach	Minimum	Median	Maximum	Mean ± SD	1st Quartile	3rd Quartile
Approach i)
Liver	2	41	199,156	279.19 ± 2442.20	12	124
Muscle	2	55	199,974	455.65 ± 3619.21	13	218
Approach ii)
Liver	2	41	199,156	281.89 ± 2457.76	12	125
Muscle	2	56	199,974	461.60 ± 3650.29	13	221
Approach iii)	2	62	209,060	572.59 ± 3993.11	13	280

Approach i) non-merged samples; Approach ii) merged samples by group for low-RFI and merged samples for high-RFI for each tissue, Approach iii) merged samples by group and tissue for low- and high-RFI for both tissues

SD Standard Deviation