Table 4.

Biological pathways significantly associated with genes in which SNPs from Low- and High-RFI were localized

Pathway Name	p-value	FDRi	Genes associated with SNPs detected	Function
Low-RFIii
Members of the BCRa signaling	1.68 × 10−6	5.12 × 10−3	20	Immune
Oxytocin signaling	1.70 × 10−5	1.87 × 10−2	42	Reproduction and Metabolism
EPHA2b forward signaling	2.72 × 10−5	1.87 × 10−2	10	Growth and Metabolism
High-RFI
Members of the BCR signaling	1.21 × 10−5	1.52 × 10−2	19	Immune
B cell activation	1.313 × 10−5	1.52 × 10−2	22	Immune
Regulation of RAC1c activity	1.48 × 10−5	1.52 × 10−2	17	Metabolism

ⁱ FDR False Discovery Rate

ⁱⁱ Top 3 pathways out of 111 significantly associated pathways

^a BCR B Cell Receptor

^b EPHA2 Ephrin type-A receptor 2

^c RAC1 Ras-related C3 botulinum toxin substrate 1