Table 2.
Multivariable linear regression of cognitive and physical functions by Aβ+NfL+ conditions
| Parameters | Aβ+NfL+ group (all participants) # | Aβ+NfL+ group (with APOE)# | ||||||
|---|---|---|---|---|---|---|---|---|
| Coefficient | p | Adjusted p∆ | 95%CI | Coefficient | p | Adjusted p∆ | 95%CI | |
| Initial CCS | − 0.19 | 0.11 | 0.45 | (− 0.42, 0.04) | − 0.15 | 0.24 | 0.85 | (− 0.39, 0.10) |
| Initial MMSE | − 0.02 | 0.93 | 0.93 | (− 0.60, 0.55) | − 0.03 | 0.92 | 0.92 | (− 0.57,0.64) |
| Initial gait speed (m/s) | − 0.01 | 0.87 | 0.93 | (− 0.08, 0.07) | − 0.02 | 0.63 | 0.85 | (− 0.10, 0.06) |
| Initial chair-stand time (s) | 0.34 | 0.61 | 0.93 | (− 1.00, 1.69) | 0.50 | 0.50 | 0.85 | (− 0.95, 1.94) |
Covariates: age, sex, body mass index, education level and MAPT group
#Participants without Aβ+NfL+ condition as the reference
∆p value adjusted by Benjamini–Hochberg procedure