Table 1.
Associations of RIPK1 and TLR3 expression with clinicopathological parameters of CCA patients
| TLR3 | Chi square | p-value | RIPK1 | Chi square | p-value | ||||
|---|---|---|---|---|---|---|---|---|---|
| Gender | n (%) | Low | High | Low | High | ||||
| Male | 54 (39%) | 22 | 30 | 0.103 | 0.748 | 26 | 26 | 1.059 | 0.303 |
| Female | 35 (61%) | 14 | 22 | 22 | 14 | ||||
| Age (years) | |||||||||
| < 67 | 44 (50%) | 19 | 25 | 0.188 | 0.665 | 28 | 16 | 2.933 | 0.087 |
| > = 67 | 44 (50%) | 17 | 27 | 20 | 24 | ||||
| Grading | |||||||||
| well differentiated | 13 (14.8%) | 4 | 11 | 3.152 | 0.207 | 9 | 6 | 0.277 | 0.893 |
| moderately differentiated | 73 (83%) | 32 | 39 | 38 | 33 | ||||
| poorly differentiated | 2 (2.2%) | 0 | 2 | 1 | 1 | ||||
| Tumor size (mm) | |||||||||
| < 35 | 30 (38.5%) | 14 | 35 | 5.727 | 0.030 | 27 | 22 | 0.119 | 0.730 |
| > = 35 | 48 (61.5%) | 20 | 17 | 19 | 18 | ||||
| Perineural Invasion | |||||||||
| Present | 65 (73%) | 22 | 43 | 5.132 | 0.023 | 43 | 22 | 13.517 | 0.0002 |
| None | 24 (27%) | 14 | 9 | 5 | 18 | ||||
| Vascular Invasion | |||||||||
| Present | 66 (74.2%) | 21 | 45 | 9.026 | 0.003 | 41 | 25 | 6.111 | 0.013 |
| None | 23 (25.8%) | 15 | 7 | 7 | 15 | ||||
| Lymph node invasion | |||||||||
| Present | 62 (69.7%) | 19 | 43 | 9.145 | 0.002 | 40 | 22 | 8.414 | 0.004 |
| None | 27 (30.3%) | 17 | 9 | 8 | 18 | ||||