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. 2020 Sep 18;10(25):11549–11561. doi: 10.7150/thno.44251

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CXCR4 inhibits cell apoptosis and promotes G2/M arrest. (A) AGS-EBV cells grown in the presence or absence of siCXCR4 were incubated with either rapamycin or DMSO for the last 6 h of the total incubation time. Apoptosis was measured by Annexin V/PI staining. Representative data are shown as the mean ± SD. (B) PI staining was used to determine the distribution of G2/M cells in the siCXCR4, siCXCR4+rapamycin, rapamycin, DMSO and control groups. Representative data are shown as the mean ± SD.