Figure 5.

CLU-TAK1-NF-κB signaling axis is clinically relevant. (A) Schematic model of CLU-TAK1-NF-κB signaling axis in lung cancer. (B) Correlation analysis of expression between CLU and TAK1. Expression data of lung adenocarcinoma cancer patients from TCGA data base (analyzed through UCSC Xena). (C) and (D) Correlation analysis between CLU and NF-κB target gene IL1B and IL6. (E) and (F) Correlation analysis between CLU and NF-κB target gene IL1B and IL6 in lung adenocarcinoma cancer patients positive of KRAS mutation. Pearson r and P value are shown in images. Date are presented as log2 RSEM. P value and Person r were shown on the figure.