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. 2020 Sep 26;10(25):11837–11861. doi: 10.7150/thno.49784

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Schematic illustration showing the applications of NIR light-responsive nanomaterials, NIR light-responsive bone scaffolds, and NIR light-triggered drug delivery systems for bone cancer therapy. The NIR light-responsive nanomaterials (A) and scaffolds (B) with the specific features of highly efficient photothermal conversion and controllable ROS release provide an effective biomaterial platform for the phototherapy of bone cancers. C. The NIR light-triggered drug delivery systems can realize controlled release of the encapsulated anti-tumor drugs for bone cancer chemotherapy. NIR, near infrared; ROS, reactive oxygen species.