Fig.6. CARD9 expression in DCs is critical for development of autoimmunity and colitis in DC-specific lyn deficient mice.
(A to D) Serum was collected from the indicated mice at 6 months of age. The amount of antibody to ssRNA or dsDNA in the serum was analyzed by ELISA. (E and F) Cells were harvested from spleens of indicated mice at 3 months of age, stained with fluorescently labeled antibodies and analyzed by flow cytometry using the gating strategy shown in fig. S7. * p<0.05, **p<0.01, one way ANOVA with Tukey HSD test, each bar represents an n of 5-10 mice per group. Results are representative of at least 2 independent experiments.