Table 1.
Laboratory data, respiratory function, and mechanical ventilation†
| Variable | Reference range, adults | On admission | ICU day 3 | ICU day 7 | ICU day 14 |
|---|---|---|---|---|---|
| White blood cell (109/L) | 4.50–9.80 | 9.58 | 13.99 | 24.14 | 23.58 |
| C-reactive protein (mg/L) | 0.0–5.0 | 137 | 77.7 | 138 | 121 |
| Procalcitonin (mcg/L) | 0.00–0.25 | 1.37 | 2.09 | 1.67 | 2.07 |
| IL (interleukin)-6 (ng/L) | < 3.4 | 491 | 32.7 | NA | NA |
| Ferritin (mcg/L) | 30–400 | 605 | 378 | NA | NA |
| D-Dimer (mcg/L) | 0.00–500.0 | 1605 | 810 | 3497 | 6941 |
| Fibrinogen (g/L) | 2.00–4.00 | 6.10 | 3.84 | 6.06 | 8.47 |
| Activated partial-thromboplastin time (sec) | 28.0–40.0 | 39 | 27.3 | 33.6 | 32.2 |
| Creatinine (mg/dL) | 0.51–0.95 | 2.4 | 5 | 2.9 | 2.6 |
| Urea nitrogen (mg/dL) | 21–54 | 90 | 172 | 135 | 167 |
| Lactate dehydrogenase (U/L) | 135–214 | 425 | 282 | 357 | 265 |
| Arterial pH | 7.35–7.45 | 7.36 | 7.35 | 7.23 | 7.34 |
| Arterial partial pressure of oxygen (mmHg) | 83–108 | 71.8 | 73.3 | 80.8 | 56.1 |
| Arterial partial pressure of carbon dioxide (mmHg) | 32–45 | 42.4 | 48.1 | 54.1 | 55.4 |
| Lactate (mmol/L) | 0.5–1.6 | 1.1 | 1.1 | 1.6 | 0.8 |
| Nasopharyngeal swab | Positive-quite positive-negative | Positive | Positive | Positive | Quite positive |
| Ventilation mode | Controlled | Controlled | Controlled | Assisted | |
| Fraction of inspired oxygen | 0.8 | 0.6 | 0.6 | 0.6 | |
| Positive end-expiratory pressure (cmH2O) | 15 | 15 | 13 | 12 | |
| Continuous renal replacement therapy | NO | YES | YES | YES |
†To convert the values for urea nitrogen to millimoles per liter, multiply by 0.357. To convert values for creatinine to micromoles per liter, multiply by 88.4. NA denotes not available