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. 2020 Aug 5;12(13):997–1006. doi: 10.2217/imt-2020-0075

Table 1. . Clinical characteristics of 14 relapsed or refractory diffuse large B-cell lymphoma patients.

n Gender Age Diagnosis Disease status before ASCT Sites of active disease Conditioning therapy MNC cell dose
(×108/kg)
CD34 cell dose
(×106/kg)
CAR T-cell dose
(×106/kg)
CRS max grade Best response Duration of best response (month)
1 F 47 DLBCL SD Multiple LN CEAC 4.60 0.44 0.74 1 CR 2.43
2 F 52 DLBCL SD Multiple LN CEAC 4.61 1.15 3 1 CR 8.31+
3 M 32 DLBCL PD Pelvic LN CEAC 7.14 1.14 1.2 2 PD 1.35
4 M 68 DLBCL SD Abdomen LN CEAC 5.94 2.37 2.14 1 CR 20.4+
5 M 44 DLBCL PD Abdomen LN R-CEAC 8.45 12.26 0.88 N PD 3.65
6 M 28 DLBCL Relapse Multiple LN CEAC 5.06 5.06 7.89 2 CR 16.07+
7 F 56 DLBCL PD Breast CEAC 3.60 4.11 2.37 2 PR 14.82
8 M 22 DLBCL SD Cervical LN R-CEAC 4.72 1.65 1.5 1 PD 5.62
9 F 44 DLBCL SD Abdomen LN R-CEAC 4.70 12 2.49 N PR 9.88+
10 M 27 DLBCL PD Mediastinum R-CEAC 4.50 7 1.72 2 PR 11.4+
11 F 37 DLBCL SD Abdomen LN R-CEAC 3.51 2.12 5 3 CR 10.91+
12 M 19 DLBCL PD Multiple LN CEAC 7.54 2.76 6.32 2 CR 7.75+
13 M 39 DLBCL SD Abdomen LN CEAC 5.69 6.67 3.59 1 PR 6.6+
14 M 56 DLBCL PD Mediastinum R-CEAC 8.72 5.6 3 2 PR 1.81

ASCT: Autologous hematopoietic stem cell transplantation; CAR: Chimeric antigen receptor; CEAC: Semustine, cytarabine, etoposide and cyclophosphamide; CR: Complete remission; CRS: Cytokine-release syndrome; DLBCL: Diffuse large B-cell lymphoma; F: Female; LN: Lympho nod; M: Male; MNC: Mononuclear cell; N: No CRS; PD: Progressive disease; PR: Partial remission; R: Rituximab; SD: Stable disease.