Table II.
N | Median OS (95% CI), months | HR (95% CI) | Log-rank test P value | Adjusted HR (95% CI)* | Wald test P value* | |
---|---|---|---|---|---|---|
Sex | ||||||
Male | 1479 | 28 (24, 33) | Reference | 0·47 | Reference | 0·39 |
Female | 1215 | 27 (22, 32) | 1·04 (0·93, 1·17) | 0·95 (0·84, 1·07) | ||
Age at diagnosis, years | ||||||
18–39 | 917 | NE (58, NE) | Reference | <0·001 | Reference | <0·001 |
40–49 | 420 | 33 (25, NE) | 1·50 (1·24, 1·82) | 1·58 (1·30, 1·93) | ||
50–59 | 503 | 23 (18, 33) | 1·78 (1·49, 2·12) | 1·92 (1·59, 2·32) | ||
60–69 | 471 | 20 (16, 23) | 2·18 (1·84, 2·59) | 2·48 (2·06, 2·99) | ||
70+ | 383 | 8 (6, 10) | 3·84 (3·24, 4·55) | 4·74 (3·93,5·72) | ||
Race/ethnicity | ||||||
Non-Hispanic White | 1367 | 28 (24, 33) | Reference | 0·090 | Reference | 0·009 |
African American | 173 | 21 (16, 27) | 1·14 (0·91, 1·43) | 1·43 (1·13, 1·83) | ||
Asian | 194 | NE (24, NE) | 0·78 (0·61, 1·00) | 0·93 (0·70, 1·23) | ||
Hispanic | 928 | 26 (22, 33) | 0·94 (0·82, 1·06) | 1·22 (1·04, 1·43) | ||
Native American | 28 | 17 (10, NE) | 1·21 (0·73, 2·03) | 1·56 (0·91, 2·68) | ||
Unknown | 4 | NE | NE | NE | ||
Married | ||||||
Yes | 1323 | 34 (28, 42) | Reference | 0·003 | Reference | 0·19 |
Not | 1371 | 23 (21, 27) | 1·19 (1·06, 1·33) | 1·09 (0·96, 1·23) | ||
Insurance | <0·001 | |||||
Insured | 1812 | 28 (24, 33) | Reference | 0·60 | Reference | |
Any medicaid | 675 | 25 (20, 31) | 1·06 (0·92, 1·21) | 1·40 (1·20, 1·64) | ||
Uninsured/unknown | 207 | 30 (21, NE) | 0·95 (0·76, 1·19) | 1·25 (0·99, 1·58) | ||
Year of diagnosis | ||||||
2010 | 529 | 23 (18, 30) | Reference | 0·18 | Reference | 0·33 |
2011 | 553 | 28 (23, 33) | 0·90 (0·77, 1·05) | 0·94 (0·80, 1·10) | ||
2012 | 526 | 28 (23, NE) | 0·90 (0·76, 1·06) | 0·92 (0·78, 1·09) | ||
2013 | 542 | NE | 0·89 (0·75, 1·07) | 0·88 (0·74, 1·06) | ||
2014 | 544 | NE | 0·76 (0·59, 0·98) | 0·77 (0·60,0·99) | ||
Ph status | ||||||
Ph+ | 206 | 32 (18, NE) | Reference | 0·34 | Reference | 0·63 |
Ph− | 2488 | 27 (24, 30) | 1·12 (0·88, 1·42) | 1·06 (0·83, 1·37) |
CI, confidence interval; HR, hazard ratio; NE, not reached or not evaluable.
Based on the Cox multivariate regression model adjusted variables included in the table and stratified by SEER registry site.