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. 2020 Oct 9;1(7):100115. doi: 10.1016/j.patter.2020.100115

Figure 1.

Figure 1

Illustration of a Gene Expression Dataset and Two Questions to Be Addressed by Hypothesis Testing and Binary Classification, Respectively

Hypothesis testing uses all the available instances to address a feature-related question: is a gene a biomarker with different expression levels in healthy and diseased patients? Binary classification answers an instance-related question: is a patient diseased?