| SCL/TAL1 |
master regulator of the adult hematopoietic (Courtial et al., 2012; Wehrspaun, Haerty & Ponting, 2015) |
| VEGF |
master regulator of mucosal immunity driving angiogenesis (Danese, 2008b) |
| PU.1 |
master regulator of hematopoiesis and bone marrow (Yang et al., 2012) |
| Sim1 |
master regulator of Drosophila neurogenesis (Eaton & Glasgow, 2006) |
| Gcm |
master regulator of nervous system development in Drosophila, parathyroid development, master regulator of expression and function regulation in mammals (Cattenoz & Giangrande, 2016) |
| FOXM1 |
master regulator of different stages of the cell cycle (Jeffery et al., 2017; Zona et al., 2014) |
| Blimp1 |
master regulator of B cell differentiation into plasma cells (John & Garrett-Sinha, 2009; Vrzalikova, Woodman & Murray, 2012) |
| Oct4 |
master regulator of embryonic stem cell self-renewal and pluripotency (Samardzija et al., 2017a) |
| Myc |
master regulator of cell performance (growth, proliferation, stem cell pluripotency, ribosomal biogenesis, etc.) (Grifoni & Bellosta, 2015; Holmberg Olausson, Nistér & Lindström, 2012; Kazan & Manners, 2013) |
| HIF |
master regulator of cellular responses to hypoxia (Liu, Semenza & Zhang, 2015; Semenza, 2014; Semenza, 2017) |
| CTCF |
master regulator of human epigenetics and genomic spatial organization (Golan-Mashiach et al., 2012) |
| FOXj1 |
master regulator of cilia generation program (Yu et al., 2008) |
| SinR |
master regulator of Bacillus subtilis biofilm formation (Chu et al., 2006; Stowe et al., 2014) |
| CtrA |
master regulator of the cell cycle of the bacillus (Gora et al., 2010; Laub et al., 2002; Pini et al., 2015) |
| FlhDC |
master regulator of flagellar genes (Chatterjee, Cui & Chatterjee, 2015; Cui et al., 2008; Stafford, Ogi & Hughes, 2005) |
| Fur |
master regulator of iron metabolism in Gram-negative bacteria (González et al., 2012; Huja et al., 2014) |
| CsgD |
master regulator of E. coli biofilm formation (Ogasawara, Yamamoto & Ishihama, 2010; Wen et al., 2017) |
| Spo0A |
master regulator of the pathogenesis of Bacillus subtilis spore formation (Fujita & Losick, 2005; Wolański & Jakimowicz, 2014) |
| CcpA |
master regulator of carbon catabolism regulation in Bacillus (Muscariello et al., 2013; Weeks et al., 2012a; Weeks et al., 2012b) |
| LuxR |
master regulator of quorum sensing (Ball, Chaparian & van Kessel, 2017; Pompeani et al., 2008) |
| WOR1 |
master regulator of white and opaque phenotypes of Candida albicans (Zhang et al., 2014) |
| P53 |
master regulator of human malignant tumors (Farnebo, Bykov & Wiman, 2010; Resnick et al., 2005) |
| P63 |
master regulator of epidermal development and differentiation (Soares & Zhou, 2018) |
| Nrf2 |
master regulator of redox homeostasis (Basak et al., 2017; Cores et al., 2020; Hayes & Dinkova-Kostova, 2017) |
| MITF |
master regulator of melanocyte development (Levy, Khaled & Fisher, 2006) |
| TFEB |
master regulator of lysosomal biogenesis and autophagy (Medina et al., 2015; Settembre et al., 2011) |
| MyoD |
master regulator of skeletal muscle gene expression programs (Aziz, Liu & Dilworth, 2010; Sunadome et al., 2014) |
| MicroRNAs (miR-10b*,miR21, miR-31,miR153, miR156, etc.) |
master regulator of gene expression in many physiological and pathological processes (Biagioni et al., 2012; Datta & Paul, 2015; Kaul & Krams, 2015; Liang et al., 2020; Miranda et al., 2010,Schmittgen, 2010; Stief et al., 2014; Voorhoeve, 2010) |
| PGC-1 α
|
master regulator of mitochondrial gene expression (Fernandez-Marcos & Auwerx, 2011; Zhu et al., 2009) |
| Prox1 |
master regulator of lymphatic endothelial cell differentiation (Hong & Detmar, 2003; Kang et al., 2010; Ke & Yang, 2017) |
| AphA |
master regulator of quorum sensing (Sun et al., 2012; Van Kessel et al., 2013) |
| PPARgamma |
master regulator of fat formation (Lehrke & Lazar, 2005a; Sunadome et al., 2014) |
| foxp3 |
master regulator of regulatory T (Treg)cell development and function (Liston, 2010; Thornton & Shevach, 2019) |
| ComK |
master regulator of late competence genes (Jaskólska & Gerdes, 2015; Ogura, Hashimoto & Tanaka, 2002) |
