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Time course (A) and maximum increment (B) in serum growth hormone (GH) above baseline after 0.375 mg of clonidine PO in controls and patients. The solid horizontal lines indicate the group mean; the shaded areas represent ± SEM. HCs, healthy control subjects; SCHs, patients with paranoid schizophrenia; SADs, patients with schizoaffective disorder; BDs, patients with bipolar depression.
