. 2020 Sep 25;11:575337. doi: 10.3389/fendo.2020.575337

Table 3.

Logistic regression analysis on the contribution of the potential predicting variables to live birth and clinical pregnancy outcomes.

Variables	Live birth						Clinical pregnancy
Variables	OR (95% CI)	P-value	Adjusted OR(95% CI)^a	P-value^a	Adjusted OR(95% CI)^b	P-value^b	OR (95% CI)	P-value	Adjusted OR(95% CI)^a	P-value^a	Adjusted OR(95% CI)^b	P-value^b
PCOS diagnosis	1.287 (1.093−1.514)	0.002	1.213 (1.027−1.433)	0.023	1.012 (0.852−1.204)	0.888	1.639 (1.377−1.950)	<0.001	1.532 (1.284−1.830)	<0.001	1.248 (1.038−1.501)	0.019
Maternal age (y)	0.959 (0.947−0.971)	<0.001	0.960 (0.948−0.972)	<0.001	0.983 (0.968−0.997)	0.021	0.971 (0.959−0.984)	<0.001	0.972 (0.960−0.985)	<0.001	0.993 (0.978−1.008)	0.333
Maternal BMI (kg/m²)	0.999 (0.983−1.016)	0.946	1.004 (0.987−1.021)	0.677	0.996 (0.979−1.014)	0.667	1.021 (1.004−1.038)	0.014	1.020 (1.002−1.037)	0.026	1.008 (0.990−1.027)	0.362
Infertility duration (y)	0.974 (0.957−0.991)	0.003			0.989 (0.971−1.008)	0.271	0.986 (0.969−1.004)	0.126			0.996 (0.977−1.016)	0.707
Total dose of gonadotropin (IU)¹	0.718 (0.679−0.759)	<0.001			0.798 (0.750−0.850)	<0.001	0.682 (0.645−0.722)	<0.001			0.753 (0.707−0.802)	<0.001
Serum E₂ level (pg/ml) on hCG day²	1.057 (1.028−1.087)	<0.001			0.968 (0.936−1.001)	0.058	1.045 (1.016−1.075)	0.002			0.939 (0.907−0.972)	<0.001
EMT (mm) on hCG day	1.087 (1.066−1.109)	<0.001			1.091 (1.069−1.114)	<0.001	1.087 (1.065−1.109)	<0.001			1.092 (1.070−1.115)	<0.001
No. of fertilized occytes	1.050 (1.041−1.060)	<0.001			1.030 (1.018−1.041)	<0.001	1.057 (1.047−1.067)	<0.001			1.037 (1.025−1.049)	<0.001
No. of embryos transferred	0.880 (0.821−0.943)	<0.001			1.009 (0.930−1.095)	0.830	0.952 (0.888−1.021)	0.169			1.115 (1.026−1.211)	0.010
Embryo type
Cleavage embryo	Ref	Ref			Ref	Ref	Ref	Ref			Ref	Ref
Blastocyst	2.005 (1.667−2.410)	<0.001			1.951 (1.603−2.376)	<0.001	2.126 (1.753−2.578)	<0.001			2.210 (1.797−2.719)	<0.001
Embryo quality
Cycle with high-quality embryos	Ref	Ref			Ref	Ref	Ref	Ref			Ref	Ref
Cycles without high-quality embryos	0.209 (0.161−0.272)	<0.001			0.257 (0.197−0.336)	<0.001	0.210 (0.166−0.267)	<0.001			0.270 (0.211−0.345)	<0.001

All the variables inputted in the model were shown in Table 3. BMI, body mass index; CI, confidence interval; OR, odds ratio; E₂,estradiol; hCG, human chorionic gonadotropin; EMT, endometrial thickness; Ref, reference; ¹per 1,000 IU increased; ²per 1,000 pg/ml increased.

Adjusted for maternal age and BMI.

Adjusted for maternal age, BMI, infertility duration, total dose of gonadotropin, serum E₂ level and endometrial thickness on hCG day, number of fertilized occytes, number of embryos transferred, embryo type and embryo quality.