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. 2020 Sep 25;8:590581. doi: 10.3389/fcell.2020.590581

TABLE 1.

Summary of base editing efficiency.

Gene Mutation Total number of clones Heterozygous clones Homozygous clones
KCNQ1 L114P 52 26 (50%) 3 (5.8%)
KCNQ1 R190Q 77 22 (28.6%) 6 (7.8%)
KCNH2 Y616C 4 4 (100%) 0 (0)
KCNH2 Y475C 41 18 (40.9%) 8 (19.5%)
SCN5A E1784K 107 32 (29.9%) 5 (4.7%)
SCN5A R1879W 47 2 (4.3%) 8 (17%)