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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Nature. 2020 Sep 23;586(7827):145–150. doi: 10.1038/s41586-020-2761-3

Extended Data Figure 5 -. CryoEM Density for all compounds bound to the E coli ribosome.

Extended Data Figure 5 -

a, 2.6-Å CryoEM structure of VM2 bound to the 50S subunit of the E. coli ribosome. Coulomb potential density is contoured in dark blue at 4.0𝜎 and light gray at 1.0𝜎 for entire figure. b, 2.8-Å CryoEM structure of 21 bound to the 50S subunit of the E. coli ribosome. c, 2.8-Å CryoEM structure of 40e bound to the 50S subunit of the E. coli ribosome. d, 2.5-Å CryoEM structure of 40o bound to the 50S subunit of the E. coli ribosome. e, 2.8-Å CryoEM structure of 40q bound to the 50S subunit of the E. coli ribosome. f, 2.6-Å CryoEM structure of 41q bound to the 50S subunit of the E. coli ribosome. g, 2.5-Å CryoEM structure of 46 bound to the 50S subunit of the E. coli ribosome. h, 2.5-Å CryoEM structure of 47 bound to the 50S subunit of the E. coli ribosome. i, 2.7-Å CryoEM structure of 46/VS1 bound to the 50S subunit of the E. coli ribosome. j, 2.8-Å CryoEM structure of 47/VS1 bound to the 50S subunit of the E. coli ribosome.