Table 2.

Metabolites with Significant Relative Flux Difference between Myc-On and Myc-Off Cells

metabolites	Myc-On	Myc-Off	p	FCa
acetyl-l-glutamine	16.7 ± 0.9	57.8 ± 8.3	0.002	0.29
aconitate	76.0 ± 9.2	468.9 ± 97.4	0.004	0.16
alanine	67416.3 ± 3769.3	492002.7 ± 63432.7	0.0009	0.14
citrate	1168.3 ± 65.6	7488.0 ± 1385.5	0.003	0.16
cytidine	10.6 ± 1.1	878.0 ± 212.3	0.004	0.01
dCDP	47.3 ± 2.8	512.2 ± 49.6	0.0003	0.09
fructose	1025.9 ± 87.8	2142.1 ± 127.4	0.00002	0.48
sarcosine	68655.1 ± 4338.6	196243.0 ± 11649.0	0.00005	0.35
adenosine	20.2 ± 3.2	0.2 ± 0.2	0.001	99.15
adenosyl-l-homocysteine	406.3 ± 52.0	18.0 ± 10.4	0.0005	22.53
ADP	8212.1 ± 794.4	236.0 ± 31.7	0.0003	34.80
AMP	8363.1 ± 601.3	148.3 ± 13.3	0.0001	56.40
ATP	2574.2 ± 245.6	364.6 ± 39.1	0.0003	7.06
fructose 6-phosphate	13758.9 ± 1573.1	1751.5 ± 282.4	0.0005	7.86
G16BP	13206.5 ± 949.9	4038.6 ± 1093.9	0.00002	3.27
GDP	400.0 ± 30.3	32.6 ± 11.7	0.00003	12.27
glutamine	73176.0 ± 6580.4	23324.5 ± 2489.7	0.0002	3.14
reduced glutathione	13195.2 ± 1356.1	979.4 ± 996.1	0.00001	13.47
hydroxyproline	14657.2 ± 1208.7	4784.8 ± 348.3	0.0002	3.06
l-ascorbic acid	492.3 ± 16.7	167.8 ± 16.1	0.0000001	2.93
NAD	2814.0 ± 77.3	566.5 ± 31.2	0.0000008	4.97
NADH	19.7 ± 3.0	3.1 ± 0.6	0.001	6.39
serine	1426.0 ± 57.6	707.6 ± 48.2	0.000002	2.02
UDP	3266.4 ± 186.5	98.1 ± 15.6	0.00005	33.28
UDP-GlcNAc	106.7 ± 6.2	30.3 ± 2.5	0.00002	3.52
xylitol	336.1 ± 17.6	92.3 ± 6.0	0.00002	3.64
1-methyladenosine	10.4 ± 1.2
acetylcarnitine	11929.6 ± 1467.6
oxidized glutathione	4575.3 ± 280.3
glycine	239.2 ± 12.5
NADP	1.3 ± 0.2
2-hydroxyglutaric acid		107.9 ± 11.8
3-phosphoglyceric acid		5568.8 ± 1099.5
N-acetylneuraminic acid		330.7 ± 159.0

^aFC: Myc-On/Myc-Off