Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 8;11(10):835. doi: 10.1038/s41419-020-03033-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a SytoxGreen assay indicated increased cell death in the Ad-U1 transduced neurons. b Immunoblotting showed autophagy activation as determined by increased LC3-II and decreased p62, when neurons expressed Ad-Tat or Ad-U1, in the absence or presence of bafilomycin A1 50 nM. c Immunoblotting showed increased apoptosis in neurons expressing the Ad-Tat or Ad-U1 for 72h. Apoptosis marker cleaved-caspase3 was significantly increased, while the anti-apoptotic markers Bcl2 and BAG3 decreased significantly.