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. 2020 Oct 8;10:16778. doi: 10.1038/s41598-020-73440-2

Table 1.

Distribution of K. pneumoniae blaKPC-2 and blaKPC-3 isolates and resistance to meropenem.

blaKPC allele KpnCluster MLST The Netherlands Caribbean Total
Sequence type S I R S I R
blaKPC-2 KpnCluster-003 ST258 2 2
KpnCluster-005 ST258 3 3
KpnCluster-019 ST560 1 2 6 4 13
KpnCluster-021 ST144 1 2 3
KpnCluster-041 ST560 2 2
Non-KpnCluster variant 3 4 14 1 2 4 28
Subtotal 51
blaKPC-3 KpnCluster-008 ST512 4 4
KpnCluster-025 ST307 1 6 7
KpnCluster-038 ST11 2 2
KpnCluster-050 ST13 1 1 2
Non-KpnCluster variant 3 5 8 1 1 18
Subtotal 33
Total 8 12 40 10 7 7 84

Based on the clinical breakpoints according to EUCAST, the isolates were classified as sensitive (S; < 2 mg/L), intermediate (I; ≥ 2 to 8 mg/L) and resistant (R; > 8 mg/L).