Table 1.
blaKPC allele | KpnCluster | MLST | The Netherlands | Caribbean | Total | ||||
---|---|---|---|---|---|---|---|---|---|
Sequence type | S | I | R | S | I | R | |||
blaKPC-2 | KpnCluster-003 | ST258 | 2 | 2 | |||||
KpnCluster-005 | ST258 | 3 | 3 | ||||||
KpnCluster-019 | ST560 | 1 | 2 | 6 | 4 | 13 | |||
KpnCluster-021 | ST144 | 1 | 2 | 3 | |||||
KpnCluster-041 | ST560 | 2 | 2 | ||||||
Non-KpnCluster | variant | 3 | 4 | 14 | 1 | 2 | 4 | 28 | |
Subtotal | 51 | ||||||||
blaKPC-3 | KpnCluster-008 | ST512 | 4 | 4 | |||||
KpnCluster-025 | ST307 | 1 | 6 | 7 | |||||
KpnCluster-038 | ST11 | 2 | 2 | ||||||
KpnCluster-050 | ST13 | 1 | 1 | 2 | |||||
Non-KpnCluster | variant | 3 | 5 | 8 | 1 | 1 | 18 | ||
Subtotal | 33 | ||||||||
Total | 8 | 12 | 40 | 10 | 7 | 7 | 84 |
Based on the clinical breakpoints according to EUCAST, the isolates were classified as sensitive (S; < 2 mg/L), intermediate (I; ≥ 2 to 8 mg/L) and resistant (R; > 8 mg/L).